NCCS’ novel approach improves success rate of bone marrow transplantation


Currently, haematopoietic stem cells (HSCs) taken from older donors for bone marrow transplantation have lower efficiency and capacity to engraft in recipients thus limiting their usefulness. But all this is set to change. Researchers from Pune’s National Centre for Cell Science (NCCS) have found novel ways to rejuvenate the haematopoietic stem cells taken from aged donors and restore their functionality prior to transplantation to improve their engrafting efficiency.

A team led by Dr. Vaijayanti Kale from the Stem Cell Lab at NCCS co-cultured aged haematopoietic stem cells and young mesenchymal stromal cells for 36 hours. The brief exposure was sufficient to rejuvenate the stem cells and improve their functionality....Read more

 

Source web page:The Hindu


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